Thursday, September 12, 2019

Oxycodone Research Paper Example | Topics and Well Written Essays - 1000 words

Oxycodone - Research Paper Example OxyContin is a brand for single-ingredient oxycodone with time-release mechanism. OxyContin was approved by U.S. Food and Administration in 1995 and became available in the market in 1996. Oxycodone belongs to the Schedule II class or controlled substance which means it has high abuse potential. It causes physical and psychological dependence that people often misuse the drug. Oxycodone is a potent pain killer similar to heroin. It elevates dopamine, a neurotransmitter in the brain that causes pleasurable experiences or euphoria. It also creates artificial endorphins, a chemical that binds receptors in the brain that gives one a â€Å"feel good† effect. It causes elation because the body cannot properly absorb the drug. Some illicit users abuse this drug to experience this euphoric high. Oxycodone is misused in different ways: snorting the powder by crushing the pill, chewing it, and injecting the solution by crushing and dissolving the tablets in water. These methods defeat t he time-release mechanism in OxyContin that causes the active ingredient to take full effect after ingestion. This dramatically increases the risk for overdose. Like other opiates, oxycodone has side-effects that can impair both mental and physical abilities. Common side-effects include nausea, dizziness, lightheadedness, seizures, constipation, blanking of emotions, and mental clouding. Acute overdose also can produce irregular breathing or respiratory depression, respiratory arrest, skeletal muscle flaccidity, low blood pressure and heart rate, coma, and death due to cardiac arrest or slowed breathing. For the last 20 years, oxycodone has been the most abused prescription drug. Oxycodone is highly addictive because use over a long period of time (from several weeks to months) leads to tolerance and the need for higher doses to reach desired effects. Because of its affects similar to morphine and heroin, oxycodone appeals to morphine and heroin users. Some even call it hillbilly he roin. When users stop taking oxycodone, they can experience withdrawal symptoms. These include anxiety, insomnia, nausea, fever, and flu-like symptoms. Like other narcotics, oxycodone is regulated by the Drug Enforcement Administration (DEA). It is an expensive drug when acquired illegally on the black market. Prices may range from $25-50 for a 50 mg. tablet. However, with more generic brands becoming available, it may cost $5-10 per pill. To prevent abuse or excessive use and decrease toxicity, new formulations are being developed. Currently undergoing clinical trials is a new drug called Remoxy. Drug users will go through great lengths to get the drugs. People would sometimes steal the drugs if they didn’t have the money to buy them. There was an incident in South Berwick, Maine, where someone got arrested for robbing three pharmacies for OxyContin. Sometimes, people would get illegal prescriptions of OxyContin. Doctors can also be part of this crime. In Winnepeg, a physici an’s license was revoked for recklessly prescribing OxyContin and Percocet. To satisfy his own addiction, he used his patients to acquire large quantities of narcotics. One woman in Florida was arrested for 23 counts of doctor shopping. She obtained 69 prescriptions from six different doctors who

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